Compound library / GLP-1s & weight loss / Fat Loss / GLP-1

Retatrutide

Triple GIP/GLP-1/glucagon receptor agonist in late-stage clinical trials, showing substantial weight-loss results.

CategoryFat Loss / GLP-1
Regulatory standingNo approved product cited
Typical routeSubcutaneous
Half-life~6 days
Common dose rangeTrial dosing varies, not yet commercially approved
Typical cycle lengthNot yet established outside trials

BioHack Track models Retatrutide at a half-life of 144 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.

No approved product cited

No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.

Reconstitution

Not yet commercially available outside clinical trials.

Storage

N/A — investigational.

Cautions

Still investigational as of this writing; not FDA-approved. Any access outside trials carries unknown sourcing/purity risk.

Track Retatrutide in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Fat Loss / GLP-1

What the evidence says

Evidence Check asks 10 questions about every compound. For Retatrutide it can answer 1 of them, from the papers we hold — graded by how strong the study design is, not by whether the findings are flattering. These are the same verdicts the app gives.

Strongest EvidenceWeight loss

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Efficacy and Safety of GLP-1 Receptor Agonists, Dual Agonists, and Retatrutide for Weight Loss in Adults With Overweight or Obesity: A Bayesian NMASystematic Review · Obesity (Silver Spring) · 2025 · PMID 40685589
  • Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trialsMeta-Analysis · Proc (Bayl Univ Med Cent) · 2025 · PMID 40291085
  • Efficacy and safety of retatrutide for the treatment of obesity: a systematic review of clinical trialsSystematic Review · J Basic Clin Physiol Pharmacol · 2025 · PMID 40728138

Look up the research

These open a search of each database for Retatrutide — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out

Selected published studies

8 papers naming Retatrutide in the title, drawn from PubMed and limited to reviews, meta-analyses and trials. Each was checked against PubMed’s own record for its title, journal and year. This is a starting point, not an evidence review — nothing here is offered as support for the dose range above, and the list is not exhaustive. See the editorial policy.

Where these figures come from

The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.

These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.

Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.

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