Compound library / GLP-1s & weight loss / Fat Loss / GLP-1

Exenatide (Byetta/Bydureon)

One of the earliest GLP-1 receptor agonists, derived from a compound in Gila monster venom; FDA-approved for type 2 diabetes.

CategoryFat Loss / GLP-1
Regulatory standingNo approved product cited
Typical routeSubcutaneous
Half-life~2.4 hours (immediate-release); weeks for extended-release
Common dose range5-10 mcg twice daily (Byetta) or 2 mg once weekly (Bydureon)
Typical cycle lengthOngoing under medical supervision

BioHack Track models Exenatide (Byetta/Bydureon) at a half-life of 2.4 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.

No approved product cited

No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.

Reconstitution

Supplied pre-filled; extended-release requires mixing powder with diluent immediately before injecting.

Storage

Refrigerate pens; some stable at room temperature short-term per label.

Cautions

Prescription medication. GI side effects common; same pancreatitis and thyroid C-cell warnings as other GLP-1 drugs.

Track Exenatide (Byetta/Bydureon) in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Fat Loss / GLP-1

What the evidence says

Evidence Check asks 10 questions about every compound. For Exenatide (Byetta/Bydureon) it can answer 2 of them, from the papers we hold — graded by how strong the study design is, not by whether the findings are flattering. These are the same verdicts the app gives.

Some Clinical EvidenceCognition

Clinical trials in humans have looked at this.

  • A Pilot Study of Exenatide Actions in Alzheimer's DiseaseRandomized Controlled Trial · Curr Alzheimer Res · 2019 · PMID 31518224
Some Clinical EvidenceMuscle growth

Clinical trials in humans have looked at this.

  • Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: the EXAMI studyRandomized Controlled Trial · Int J Cardiol · 2013 · PMID 23084550

Look up the research

These open a search of each database for Exenatide (Byetta/Bydureon) — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out

Selected published studies

10 papers naming Exenatide (Byetta/Bydureon) in the title, drawn from PubMed and limited to reviews, meta-analyses and trials. Each was checked against PubMed’s own record for its title, journal and year. This is a starting point, not an evidence review — nothing here is offered as support for the dose range above, and the list is not exhaustive. See the editorial policy.

Where these figures come from

The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.

These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.

Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.

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