Compound library / Longevity & metabolic / Longevity / Metabolic

Quercetin

Flavonoid found in plants with antioxidant, anti-inflammatory, and senolytic properties in preclinical studies; often paired with dasatinib in senolytic protocols and explored for NAD+ pathway support.

CategoryLongevity / Metabolic
Regulatory standingNo approved product cited
Typical routeOral
Half-life~1-3 hours (highly variable by formulation; poor bioavailability without co-factors)
Common dose range500-1000 mg/day for general antioxidant use; 1000-2000 mg in pulsed senolytic protocols (often with dasatinib)
Typical cycle lengthOngoing (supplement) or pulsed 2-day courses monthly (senolytic protocol)

BioHack Track models Quercetin at a half-life of 2 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.

No approved product cited

No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.

Reconstitution

Oral capsule; no reconstitution needed. Look for enhanced-bioavailability forms (phytosome, dihydrate, or liposomal).

Storage

Store at room temperature.

Cautions

Generally well tolerated; can interfere with thyroid hormone absorption and some antibiotics — separate dosing. High doses may inhibit CYP3A4 metabolism of other drugs.

Track Quercetin in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Longevity / Metabolic

What the evidence says

Evidence Check asks 10 questions about every compound. For Quercetin it can answer 5 of them, from the papers we hold — graded by how strong the study design is, not by whether the findings are flattering. These are the same verdicts the app gives.

Strongest EvidenceBone density

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Effects of Resveratrol, Curcumin and Quercetin Supplementation on Bone Metabolism-A Systematic ReviewSystematic Review · Nutrients · 2022 · PMID 36079777
Strongest EvidenceInflammation

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Quercetin as a therapeutic agent for skin problems: a systematic review and meta-analysis on antioxidant effects, oxidative stress, inflammation, wound healing, hyperpigmentation, aging, and skin cancerMeta-Analysis · Naunyn Schmiedebergs Arch Pharmacol · 2025 · PMID 39738831
Strongest EvidenceLongevity

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Quercetin as a therapeutic agent for skin problems: a systematic review and meta-analysis on antioxidant effects, oxidative stress, inflammation, wound healing, hyperpigmentation, aging, and skin cancerMeta-Analysis · Naunyn Schmiedebergs Arch Pharmacol · 2025 · PMID 39738831
Strongest EvidenceSkin & collagen

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Quercetin as a therapeutic agent for skin problems: a systematic review and meta-analysis on antioxidant effects, oxidative stress, inflammation, wound healing, hyperpigmentation, aging, and skin cancerMeta-Analysis · Naunyn Schmiedebergs Arch Pharmacol · 2025 · PMID 39738831
Strongest EvidenceWound healing

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Quercetin as a therapeutic agent for skin problems: a systematic review and meta-analysis on antioxidant effects, oxidative stress, inflammation, wound healing, hyperpigmentation, aging, and skin cancerMeta-Analysis · Naunyn Schmiedebergs Arch Pharmacol · 2025 · PMID 39738831

Look up the research

These open a search of each database for Quercetin — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out

Selected published studies

10 papers naming Quercetin in the title, drawn from PubMed and limited to reviews, meta-analyses and trials. Each was checked against PubMed’s own record for its title, journal and year. This is a starting point, not an evidence review — nothing here is offered as support for the dose range above, and the list is not exhaustive. See the editorial policy.

Where these figures come from

The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.

These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.

Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.

Published by Creative Images LLC · Last updated · Corrections: support