Coenzyme central to redox reactions and energy metabolism; injectable/IV supplementation explored for mitochondrial biogenesis, DNA repair support, and cellular energy.
BioHack Track models NAD+ at a half-life of 3 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.
No approved product cited
No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.
Reconstitution
Often supplied pre-mixed in solution; light-sensitive.
Storage
Refrigerate, protect from light.
Cautions
Can cause insomnia, anxiety, or flushing if escalated too quickly; start low and titrate.
Track NAD+ in BioHack Track. Half-life, dose range and route come
pre-filled from this library — log a dose and the app counts your vial down, models what is
in your system, and puts it on the same chart as your labs and body composition.
Evidence Check asks 10 questions about every compound. For NAD+ it can answer 5 of them, from the papers we hold — graded by how strong the study design is, not by whether the findings are flattering. These are the same verdicts the app gives.
Strongest EvidenceCognition
Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.
Supplementation with NAD+ Precursors for Treating Alzheimer's Disease: A Metabolic ApproachSystematic Review · J Alzheimers Dis · 2024 · PMID 39422945
Protective Effects of Nicotinamide Adenine Dinucleotide and Related Precursors in Alzheimer's Disease: A Systematic Review of Preclinical StudiesSystematic Review · J Mol Neurosci · 2021 · PMID 33907963
Symptom-Level Precision Neurology in Amyotrophic Lateral Sclerosis (ALS): Linking Microglial Pruning, Mitochondrial Nicotinamide Adenine Dinucleotide (NAD+) Compensation, and Autophagy Failure Across the Aging SpectrumReview · Cureus · 2026 · PMID 42164014
Some Clinical EvidenceWeight loss
Clinical trials in humans have looked at this.
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic StudyRandomized Controlled Trial · J Clin Endocrinol Metab · 2023 · PMID 36740954
Some Clinical EvidenceWound healing
Clinical trials in humans have looked at this.
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adultsRandomized Controlled Trial · Nat Commun · 2018 · PMID 29599478
Insufficient EvidenceLongevity
Only reviews or early work — not enough to say either way.
Symptom-Level Precision Neurology in Amyotrophic Lateral Sclerosis (ALS): Linking Microglial Pruning, Mitochondrial Nicotinamide Adenine Dinucleotide (NAD+) Compensation, and Autophagy Failure Across the Aging SpectrumReview · Cureus · 2026 · PMID 42164014
Insufficient EvidenceMuscle growth
Only reviews or early work — not enough to say either way.
Symptom-Level Precision Neurology in Amyotrophic Lateral Sclerosis (ALS): Linking Microglial Pruning, Mitochondrial Nicotinamide Adenine Dinucleotide (NAD+) Compensation, and Autophagy Failure Across the Aging SpectrumReview · Cureus · 2026 · PMID 42164014
Research references only. Not medical advice, and not a recommendation to take anything.
Look up the research
These open a search of each database for NAD+ — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.
9 papers naming NAD+ in the title, drawn from PubMed and limited to reviews, meta-analyses and trials. Each was checked against PubMed’s own record for its title, journal and year. This is a starting point, not an evidence review — nothing here is offered as support for the dose range above, and the list is not exhaustive. See the editorial policy.
The half-life, route and dose range on this page are compiled from published
pharmacokinetic literature, manufacturer and product monographs where one exists, and the
ranges commonly reported in clinical and research use. They are kept as a range
rather than a single figure because that is what the sources actually support — a
half-life varies with route, formulation and the person.
These are not citations, and this page is not a review of the evidence. Where a
number matters to you, follow the database links above and read the source. We say so
plainly rather than dressing a compiled reference up as one.
Nothing on this page has been reviewed by a named clinician. It is a reference for
people already tracking a protocol, not a recommendation to start one.
Published by Creative Images LLC ·
Last updated ·
Corrections: support
General reference compiled for use
inside the app, not medical advice and not a recommendation to take anything. Dose ranges are
what is commonly discussed, not a prescription. Talk to a qualified healthcare professional.