Compound library / Fat Loss / Metabolic

Tesofensine

Triple monoamine reuptake inhibitor (dopamine, norepinephrine, serotonin) originally developed for Alzheimer's/Parkinson's, repurposed in trials for obesity due to strong appetite-suppressant effects.

CategoryFat Loss / Metabolic
Typical routeOral
Half-life~8 days (very long, due to active metabolites)
Common dose range0.25-1 mg/day in published obesity trials
Typical cycle lengthTrial durations of 6+ months; not established for general use

BioHack Track models Tesofensine at a half-life of 192 hours, so every dose you log is decayed against that curve and the app shows what is still circulating — not just what you typed.

Reconstitution

Oral tablet/capsule; no reconstitution needed.

Storage

Store at room temperature.

Cautions

Not FDA-approved anywhere yet; raised heart rate and blood pressure in trials. Long half-life means side effects can persist for weeks after stopping.

Track Tesofensine in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Fat Loss / Metabolic

Look up the research

These open a search of each database for Tesofensine — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out