Compound library / Hormones & fertility / Sexual Health

Sildenafil (Viagra)

PDE5 inhibitor, the original and most widely known oral erectile dysfunction medication; works by relaxing blood vessels to improve blood flow.

CategorySexual Health
Regulatory standingNo approved product cited
Typical routeOral
Half-life~4 hours
Common dose range25-100 mg, taken roughly 30-60 minutes before sexual activity (max once daily)
Typical cycle lengthAs needed

BioHack Track models Sildenafil (Viagra) at a half-life of 4 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.

No approved product cited

No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.

Reconstitution

Oral tablet; no reconstitution needed.

Storage

Store at room temperature.

Cautions

Prescription medication. Dangerous interaction with nitrates (e.g. nitroglycerin) — never combine; can cause flushing, headache, vision changes, or low blood pressure, especially with alcohol or other blood-pressure medications.

Track Sildenafil (Viagra) in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Sexual Health

What the evidence says

Evidence Check asks 10 questions about every compound. For Sildenafil (Viagra) it can answer 1 of them, from the papers we hold — graded by how strong the study design is, not by whether the findings are flattering. These are the same verdicts the app gives.

Strongest EvidenceLibido

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysisMeta-Analysis · Int Urol Nephrol · 2017 · PMID 28741090
  • Ethnicity and age as factors in sildenafil treatment of erectile dysfunctionMeta-Analysis · Int J Clin Pract · 2017 · PMID 28439994
  • Sildenafil in women with sexual arousal disorder following spinal cord injuryRandomized Controlled Trial · Spinal Cord · 2011 · PMID 20733587

Look up the research

These open a search of each database for Sildenafil (Viagra) — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out

Selected published studies

12 papers naming Sildenafil (Viagra) in the title, drawn from PubMed and limited to reviews, meta-analyses and trials. Each was checked against PubMed’s own record for its title, journal and year. This is a starting point, not an evidence review — nothing here is offered as support for the dose range above, and the list is not exhaustive. See the editorial policy.

Where these figures come from

The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.

These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.

Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.

Published by Creative Images LLC · Last updated · Corrections: support