Compound library / Hormones & fertility / Sexual Health

Tadalafil (Cialis)

PDE5 inhibitor with a much longer duration of action than sildenafil — sometimes called "the weekend pill" — also approved at a low daily dose for ongoing use and for BPH symptoms.

CategorySexual Health
Regulatory standingNo approved product cited
Typical routeOral
Half-life~17.5 hours
Common dose range10-20 mg as needed, or 2.5-5 mg once daily for continuous use
Typical cycle lengthAs needed or ongoing (daily-dose form)

BioHack Track models Tadalafil (Cialis) at a half-life of 17.5 hours, so every dose you log is decayed against that curve and the app shows estimated active levels — not just what you typed.

No approved product cited

No FDA-approved product for this compound is cited on this page, and no approved human dose is quoted. Treat the range below as research and community practice rather than a prescribed dose.

Reconstitution

Oral tablet; no reconstitution needed.

Storage

Store at room temperature.

Cautions

Prescription medication. Same nitrate interaction warning as other PDE5 inhibitors; its long half-life means side effects (headache, back pain, flushing) can also linger longer.

Track Tadalafil (Cialis) in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in Sexual Health

What the evidence says

Evidence Check asks 10 questions about every compound. For Tadalafil (Cialis) it can answer 1 of them, from the papers we hold — graded by how strong the study design is, not by whether the findings are flattering. These are the same verdicts the app gives.

Strongest EvidenceLibido

Meta-analyses or systematic reviews exist — the highest grade of evidence there is, whatever they conclude. Read them.

  • Tamsulosin plus Tadalafil compared with Tamsulosin alone for benign prostate hyperplasia in patients with or without erectile dysfunction: a meta-analysis and meta-regression of randomized controlled trialsMeta-Analysis · World J Urol · 2025 · PMID 40349279
  • Discontinuation Rates of Tadalafil Alone and in Combination with a-Blockers in the Treatment of Male Lower Urinary Tract Symptoms with or without Coexisting Erectile Dysfunction: A Systematic Review and Meta-AnalysisMeta-Analysis · Int J Clin Pract · 2022 · PMID 36419863
  • Chinese herbal medicine combined with tadalafil for erectile dysfunction: a systematic review and meta-analysisMeta-Analysis · Andrology · 2020 · PMID 31464074

Look up the research

These open a search of each database for Tadalafil (Cialis) — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out

Selected published studies

12 papers naming Tadalafil (Cialis) in the title, drawn from PubMed and limited to reviews, meta-analyses and trials. Each was checked against PubMed’s own record for its title, journal and year. This is a starting point, not an evidence review — nothing here is offered as support for the dose range above, and the list is not exhaustive. See the editorial policy.

Where these figures come from

The half-life, route and dose range on this page are compiled from published pharmacokinetic literature, manufacturer and product monographs where one exists, and the ranges commonly reported in clinical and research use. They are kept as a range rather than a single figure because that is what the sources actually support — a half-life varies with route, formulation and the person.

These are not citations, and this page is not a review of the evidence. Where a number matters to you, follow the database links above and read the source. We say so plainly rather than dressing a compiled reference up as one.

Nothing on this page has been reviewed by a named clinician. It is a reference for people already tracking a protocol, not a recommendation to start one.

Published by Creative Images LLC · Last updated · Corrections: support