Compound library / GI / Metabolic

Linaclotide (Linzess)

Guanylate cyclase-C agonist peptide, FDA-approved for irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation.

CategoryGI / Metabolic
Typical routeOral
Half-lifeMinimally absorbed systemically; acts locally in the gut
Common dose range72-290 mcg/day, per indication
Typical cycle lengthOngoing as needed for symptom control

BioHack Track models Linaclotide (Linzess) at a half-life of 0.3 hours, so every dose you log is decayed against that curve and the app shows what is still circulating — not just what you typed.

Reconstitution

Oral capsule; no reconstitution needed.

Storage

Store at room temperature; keep in original container away from moisture.

Cautions

Prescription medication; not for use in patients under 6 (risk of serious dehydration); take on an empty stomach per label.

Track Linaclotide (Linzess) in BioHack Track. Half-life, dose range and route come pre-filled from this library — log a dose and the app counts your vial down, models what is in your system, and puts it on the same chart as your labs and body composition.

Others in GI / Metabolic

Look up the research

These open a search of each database for Linaclotide (Linzess) — they are not citations, and nothing here is evidence for any particular dose. The same links are in the app.

Work it out